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Senin, 14 Maret 2011

Candidas dan penatalaksanaannya

species candidas yang biasa menyerang manusia adalah:
1. Candida albicans,
2. Candida (Torulopsis)glabrata,
3. Candida parapsilosis,
4. Candida tropicalis,
5. Candida krusei,
6. Candida kefyr,
7. Candida guilliermondii,
8. Candida lusitaniae,
9. Candida stellatoidea, dan
10.Candida dubliniensis.

ABSTRAK
Kandidiasis oral adalah infeksi pada mukosa rongga mulut yang disebabkan oleh Candida, paling sering disebabkan oleh Candida Albicans dan juga merupakan fungi yang paling sering ditemukan menginfeksi tubuh manusia. Kandidiasis oral dapat juga disebabkan oleh non Candida albicans Candida (NCAC) , dimana mempunyai manifestasi klinis yang sama, yang membedakan hanya sifat invasif masing-masing dan respon terhadap obat-obat anti fungi. C. tropicalis merupakan spesies NCAC yang mempunyai virulensi paling tinggi karena mempunyai kemampuan perlekatan pada sel-sel epitelial secara invitro dan mensekresi proteinase dalam level sedang. Candida tropicalis juga merupakan spesies Candida nomor dua yang paling sering dijumpai koloninya pada manusia. Penelitian melaporkan C.tropicalis sebagai penyebab kandidiasis oral dapat diidentifikasi 16% pada pasien rawat inap, yang dipicu karena adanya tekanan dari penggunaan obat-obat anti fungi khusus ataupun akibat penggunaan antibiotika sistemik. Laporan kasus ini membahas terjadinya kandidiasis oral pada penderita pria dewasa dengan median rhomboid glositis karena pemakaian antibiotik spektrum luas serta kortikosteroid topikal dengan dosis yang tidak tepat. Dengan pemeriksaan mikologi indirek didapatkan infeksi C. tropicalis. Penatalaksanaan kandidiasis oral ini yang pertama adalah mengeliminasi faktor predisposisi, optimalisasi oral hiegiene serta pemberian terapi obat kumur Chlorhexidine gluconate 0,25 % akan memberikan prognosa yang baik.

ABSTRACT
Oral candidiasis is oral mucosal infectious caused by Candida albicans or non-candida albicans candida (NCAC). Each Candida species infection have same clinical manifestation, the different only invasive nature and antifungi response. C. tropicalis is most virulence NCAC because the most adherence ability to epithelial cells in vitro as well as medium level proteinase secretion. In addition, C. topicalis is the second most common colony on human. A study reported of C. tropicalis as causa of 16 % hospitalized oral candidiasis, anti fungal drugs and systemic antibioitika was known as trigger factors. This
paper report and discuss oral candidiasis due to C.tropicalis in patient, adult male, with median rhomboid glossitis. The patient also used broad spectrum antibiotic and topical corticosteroid with imprecise dose.The management of this case was terminated antibiotic and corticosteroid, oral hygiene optimalization and was given 0,25% Chlorhexidine gluconate. However, oral hygiene optimalization, predisposition factors elimination, and, precise therapy would give a good prognosis.

Keywords: Kandidiasis oral, Candida tropicalis, Median rhomboid glossitis

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